Effects of ketamine analgesia on cardiorespiratory responses and survival to trauma and hemorrhage in rats
Abstract
Ketamine administration at a dose shown to alleviate pain in nonhemorrhaged rats with extremity trauma had only modest and transient effects on multiple aspects of cardiorespiratory function after both moderate (37%) and severe (50%) traumatic hemorrhages. Such effects did not alter survival.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 01, 2021
- Source ID
- 10.1152/japplphysiol.00476.2020
Entities
People
- Carmen Hinojosa-Laborde
- Harold G. Klemcke
- Kathy L. Ryan
- Lusha Xiang
- Mariam L. Calderon
- Stephen L. Crimmins
Organizations
- United States Army Institute of Surgical Research
- United States Army Medical Research and Development Command