Extracorporeal circulation impairs microcirculation perfusion and organ function
Abstract
ECC reduces microvascular perfusion, with no full recovery 24 h after ECC. HSA performed better as compared with LR in terms of FCD and venule flow, as well as venule oxygen saturation. Increases in inflammatory and damage markers in key organs were observed within all organs analyzed.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 01, 2022
- Source ID
- 10.1152/japplphysiol.00726.2021
Entities
People
- Krianthan Govender
- Pedro Cabrales
Organizations
- National Heart, Lung, and Blood Institute
- United States Department of Defense
- University of California, San Diego