Acute overventilation does not cause lung damage in moderately hemorrhaged swine

Abstract

Appropriate airway management is essential in trauma and critically ill patients. Prolonged mechanical ventilation can result in overventilation-induced lung barotrauma, but few studies have examined the consequence of acute overventilation. We investigated the outcome of hemorrhage followed by 1 h of overventilation in swine. We found that acute overventilation, as could be seen in the prehospital phase of trauma care, does not produce evidence of adverse effects on otherwise healthy lungs following moderate hemorrhage.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 01, 2021
Source ID
10.1152/japplphysiol.01048.2020

Entities

People

  • Cassandra Rodriguez
  • Ian L. Hudson
  • Kathy L. Ryan
  • Megan B Blackburn
  • Nathan Wienandt

Tags

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology
  • Trauma or Military Medicine