Systematic Review of Integrative Health Care Research: Randomized Control Trials, Clinical Controlled Trials, and Meta-Analysis
Abstract
A systematic review was conducted to assess the level of evidence for integrative health care research. We searched PubMed, Allied and Complementary Medicine (AMED), BIOSIS Previews, EMBASE, the entire Cochrane Library, MANTIS, Social SciSearch, SciSearch Cited Ref Sci, PsychInfo, CINAHL, and NCCAM grantee publications listings, from database inception to May 2009, as well as searches of the “gray literature.” Available studies published in English language were included. Three independent reviewers rated each article and assessed the methodological quality of studies using the Scottish Intercollegiate Guidelines Network (SIGN 50). Our search yielded 11,891 total citations but 6 clinical studies, including 4 randomized, met our inclusion criteria. There are no available systematic reviews/meta-analyses published that met our inclusion criteria. The methodological quality of the included studies was assessed independently using quality checklists of the SIGN 50. Only a small number of RCTs and CCTs with a limited number of patients and lack of adequate control groups assessing integrative health care research are available. These studies provide limited evidence of effective integrative health care on some modalities. However, integrative health care regimen appears to be generally safe.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2011
- Source ID
- 10.1155/2011/636134
Entities
People
- An-fu Hsiao
- Cindy Crawford
- Ian D. Coulter
- Raheleh Khorsan
Organizations
- RAND Corporation
- Samueli Institute
- Southern California University of Health Sciences
- United States Army Medical Research and Development Command
- University of California
- University of California, Irvine
- University of California, Los Angeles
- VA Long Beach Healthcare System