Height, Obesity, and the Risk of TMPRSS2:ERG-Defined Prostate Cancer
Abstract
Background: The largest molecular subtype of primary prostate cancer is defined by the TMPRSS2:ERG gene fusion. Few studies, however, have investigated etiologic differences by TMPRSS2:ERG status. Because the fusion is hormone-regulated and a man's hormonal milieu varies by height and obesity status, we hypothesized that both may be differentially associated with risk of TMPRSS2:ERG-defined disease.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 01, 2018
- Source ID
- 10.1158/1055-9965.epi-17-0547
Entities
People
- Amparo G. Gonzalez-feliciano
- Andreas Pettersson
- Claire H. Pernar
- D. R. Schmidt
- Edward L. Giovannucci
- Ericka M Ebot
- Kathryn L. Penney
- Kathryn M. Wilson
- Lorelei A. Mucci
- Massimo Loda
- Matthew G Vander Heiden
- Michelangelo Fiorentino
- Mingyang Song
- Rebecca E Graff
- Rosina T Lis
- Sarah C Markt
- Thomas U. Ahearn
- Travis Gerke
Organizations
- American Cancer Society
- Dana–Farber Cancer Institute
- H. Lee Moffitt Cancer Center & Research Institute
- Harvard Medical School
- Harvard University
- Karolinska Institutet
- Massachusetts Institute of Technology
- National Institutes of Health
- Office of the Secretary of Defense
- Prostate Cancer Foundation
- Stand Up to Cancer
- University of California, San Francisco