Detection of Head and Neck Cancer Based on Longitudinal Changes in Serum Protein Abundance
Abstract
Approximately 85% of the U.S. military active duty population is male and less than 50 years of age, with elevated levels of known risk factors for oropharyngeal squamous cell carcinoma (OPSCC), including smoking, excessive use of alcohol, and greater numbers of sexual partners, and elevated prevalence of human papilloma virus (HPV). Given the recent rise in incidence of OPSCC related to the HPV, the Department of Defense Serum Repository provides an unparalleled resource for longitudinal studies of OPSCC in the military for the identification of early detection biomarkers.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 01, 2020
- Source ID
- 10.1158/1055-9965.epi-20-0192
Entities
People
- Athena A Schepmoes
- Craig D Shriver
- George Coppit
- Joseph F Goodman
- Ju Yeon Lee
- Karin D. Rodland
- Shiv Srivastava
- Tao Liu
- Thomas L. Fillmore
- Tujin Shi
- Vladislav A Petyuk
- Wayne Cardoni
- Yi-ting Wang
Organizations
- George Washington University
- Korea Basic Science Institute
- Oregon Health & Science University
- Pacific Northwest National Laboratory
- Uniformed Services University of the Health Sciences