Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum
Abstract
Purpose: CT screening can reduce death from lung cancer. We sought to improve the diagnostic accuracy of lung cancer screening using ultrasensitive methods and a lung cancer–specific gene panel to detect DNA methylation in sputum and plasma.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 13, 2017
- Source ID
- 10.1158/1078-0432.ccr-16-1371
Entities
People
- Alejandro Stark
- Alicia Hulbert
- Andrew Yang
- Beverly Lee
- Candace Griffin
- Chen Chen
- Ignacio Jusue-torres
- James G. Herman
- John Wrangle
- Kristen Rodgers
- Malcolm V. Brock
- Peng Huang
- Stephen B. Baylin
- Stephen C. Yang
- Steven A. Belinsky
- Tza-Huei Wang
Organizations
- Central South University
- Johns Hopkins Bloomberg School of Public Health
- Johns Hopkins School of Medicine
- Johns Hopkins University
- Lovelace Respiratory Research Institute
- Medical University of South Carolina
- United States Department of Defense
- University of Pittsburgh