In Vivo Detection of HSP90 Identifies Breast Cancers with Aggressive Behavior
Abstract
Purpose: Hsp90, a chaperone to numerous molecular pathways in malignant cells, is elevated in aggressive breast cancers. We hypothesized that identifying breast cells with elevated Hsp90 activity in situ could result in early detection of aggressive breast cancers.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 14, 2017
- Source ID
- 10.1158/1078-0432.ccr-17-1453
Entities
People
- Amy Hobeika
- Brian W Pogue
- H. Kim Lyerly
- Kensuke Kaneko
- Michael A. Morse
- Philip F. Hughes
- Takuya Osada
- Timothy Haystead
- William R. Gwin
- Zachary C Hartman
Organizations
- Dartmouth College
- Duke University
- Duke University Hospital
- United States Department of Defense