MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease
Abstract
Purpose: Germline mutations within the MEIS-interaction domain of HOXB13 have implicated a critical function for MEIS–HOX interactions in prostate cancer etiology and progression. The functional and predictive role of changes in MEIS expression within prostate tumor progression, however, remain largely unexplored.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 31, 2018
- Source ID
- 10.1158/1078-0432.ccr-17-3673
Entities
People
- Angelo M De Marzo
- Calvin Vanopstall
- Donald J Vander Griend
- Erin M. Mcauley
- Gladell Paner
- Hannah Brechka
- Jorge Andrade
- Juan Manuel Vasquez
- Marc Gillard
- Misop Han
- Nimrod S. Barashi
- Raj R. Bhanvadia
- Russell Z. Szmulewitz
- Wen-ching Chan
Organizations
- National Cancer Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institutes of Health
- United States Department of Defense
- University of Chicago