Near-Infrared Dye-Labeled Anti-Prostate Stem Cell Antigen Minibody Enables Real-Time Fluorescence Imaging and Targeted Surgery in Translational Mouse Models
Abstract
The inability to intraoperatively distinguish primary tumor, as well as lymphatic spread, increases the probability of positive surgical margins, tumor recurrence, and surgical toxicity. The goal of this study was to develop a tumor-specific optical probe for real-time fluorescence-guided surgery.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1158/1078-0432.ccr-18-1382
Entities
People
- Anna M. Wu
- Chau P. Tran
- Chung Wang
- Evelyn A. Kono
- Johnny Guan
- Joyce M. Yamashiro
- Kirstin A Zettlitz
- Mo Zhang
- Naoko Kobayashi
- Robert E. Reiter
- Wen-Ting K Tsai
- Ziyue K. Jiang
Organizations
- China Medical University
- National Institutes of Health
- United States Department of Defense
- University of California, Los Angeles