Virus, Vessel, Victory: A Novel Approach to Tumor Killing
Abstract
Ovarian cancer is intimately dependent on aberrant tumor vasculature. A unique therapeutic approach combining a systemic oncolytic virus with a novel vascular-normalizing agent in ovarian cancer demonstrates the potential to enhance antitumor efficacy through improved delivery of the virus and enhanced infiltration of immune cells into the tumors.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 01, 2019
- Source ID
- 10.1158/1078-0432.ccr-18-3441
Entities
People
- Dmitriy Zamarin
- Yonina Bykov
Organizations
- Memorial Sloan Kettering Cancer Center
- United States Department of Defense
- Weill Cornell Medicine