Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas
Abstract
Intratumoral injection of oncolytic adenovirus Delta-24-RGDOX induces efficacious antiglioma immunity in syngeneic glioma mouse models. We hypothesized that localized treatment with the virus is effective against disseminated melanomas.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 15, 2019
- Source ID
- 10.1158/1078-0432.ccr-19-0405
Entities
People
- Candelaria Gomez-Manzano
- Caroline C. Carrillo
- Dong Ho Shin
- Frederick F Lang
- Hong Jiang
- Juan Fueyo
- Marta M Alonso
- Teresa T Nguyen
- Tiara L. Collier
- Verlene Henry
- Xuejun Fan
- Yanhua Yi
- Ying Yuan
Organizations
- Cancer Prevention and Research Institute of Texas
- Israel National Road Safety Authority
- National Cancer Institute
- United States Department of Defense
- University of Texas at Austin