Detection of Promoter DNA Methylation in Urine and Plasma Aids the Detection of Non–Small Cell Lung Cancer

Abstract

Low-dose CT screening can reduce lung cancer–related mortality. However, CT screening has an FDR of nearly 96%. We sought to assess whether urine samples can be a source for DNA methylation–based detection of non–small cell lung cancer (NSCLC).

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 14, 2020
Source ID
10.1158/1078-0432.ccr-19-2896

Entities

People

  • Alicia Hulbert
  • Anastasia Kottorou
  • Apurva Mallisetty
  • Bin Liu
  • Cassandra Villani
  • Chen Chen
  • Christian Ascoli
  • Enrico Benedetti
  • Ignacio Jusue-torres
  • James G. Herman
  • Julio Ricarte Filho
  • Klara Valyi-nagy
  • Kristen Rodgers
  • Kyla Holmes
  • Lawrence E. Feldman
  • Malcolm V. Brock
  • Malek G. Massad
  • Mary Pasquinelli
  • Nicole Gastala
  • Odile David
  • Robert A. Winn
  • Ron C Gaba
  • Tomoaki Ito
  • Tza-Huei Wang

Organizations

  • Central South University
  • Johns Hopkins School of Medicine
  • Johns Hopkins University
  • Juntendo University
  • Loyola University Chicago
  • United States Department of Defense
  • University of Illinois College of Medicine
  • University of Illinois at Chicago
  • University of Patras
  • University of Pittsburgh

Tags

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Oncology
  • Oncology (Cancer Research).