The State of Melanoma: Emergent Challenges and Opportunities

Abstract

Five years ago, the Melanoma Research Foundation (MRF) conducted an assessment of the challenges and opportunities facing the melanoma research community and patients with melanoma. Since then, remarkable progress has been made on both the basic and clinical research fronts. However, the incidence, recurrence, and death rates for melanoma remain unacceptably high and significant challenges remain. Hence, the MRF Scientific Advisory Council and Breakthrough Consortium, a group that includes clinicians and scientists, reconvened to facilitate intensive discussions on thematic areas essential to melanoma researchers and patients alike, prevention, detection, diagnosis, metastatic dormancy and progression, response and resistance to targeted and immune-based therapy, and the clinical consequences of COVID-19 for patients with melanoma and providers. These extensive discussions helped to crystalize our understanding of the challenges and opportunities facing the broader melanoma community today. In this report, we discuss the progress made since the last MRF assessment, comment on what remains to be overcome, and offer recommendations for the best path forward.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 07, 2021
Source ID
10.1158/1078-0432.ccr-20-4092

Entities

People

  • Adil Daud
  • Anna C Pavlick
  • Ashani T. Weeraratna
  • Bernard A. Fox
  • Brent A Hanks
  • Clara Curiel-lewandrowski
  • Darren Mays
  • David E. Fisher
  • Doug Hanniford
  • Douglas B. Johnson
  • Douglas Grossman
  • Eva Hernando
  • Geoffrey T. Gibney
  • Glenn Merlino
  • Hensin Tsao
  • Hussein A. Tawbi
  • Jeffrey A. Sosman
  • Jeffrey E Gershenwald
  • John M Kirkwood
  • Julio A. Aguirre-ghiso
  • Keith T. Flaherty
  • Kelly C Nelson
  • Laura K. Ferris
  • Maria S. Soengas
  • Meenhard Herlyn
  • Michael B Atkins
  • Pamela B. Cassidy
  • Paul B. Chapman
  • Ryan J Sullivan
  • Samir N. Khleif
  • Sancy A. Leachman
  • Sunandana Chandra
  • Susan Swetter
  • Vernon K. Sondak
  • Zeynep Eroglu

Organizations

  • Duke University Hospital
  • Georgetown University
  • Grossman School of Medicine
  • H. Lee Moffitt Cancer Center & Research Institute
  • Harvard Medical School
  • Icahn School of Medicine at Mount Sinai
  • Johns Hopkins Bloomberg School of Public Health
  • Melanoma Research Foundation
  • National Institutes of Health
  • Northwestern University
  • Ohio State University
  • Oregon Health & Science University
  • Stanford University
  • United States Department of Defense
  • University of Arizona
  • University of Pittsburgh
  • University of Texas at Austin
  • University of Utah
  • University of Utah School of Medicine
  • Vanderbilt University Medical Center
  • Weill Cornell Medicine

Tags

Readers

  • Academic Conference Management
  • Molecular and Cellular Biology
  • Oncology