A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes
Abstract
A subset of primary prostate cancer expresses programmed death-ligand 1 (PD-L1), but whether they have a unique tumor immune microenvironment or genomic features is unclear.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 24, 2021
- Source ID
- 10.1158/1078-0432.ccr-21-0121
Entities
People
- Adam G Sowalsky
- Anson T. Ku
- Carla Calagua
- Caroline S Jansen
- David B Sykes
- David J Einstein
- Haydn Kissick
- Huihui Ye
- Luke Del Balzo
- Miriam Ficial
- Olga Voznesensky
- Philip J Saylor
- Ross Lake
- Sabina Signoretti
- Scott Wilkinson
- Steven P Balk
- Taghreed Hirz
Organizations
- Beth Israel Deaconess Medical Center
- Brigham and Women's Hospital
- Dana–Farber Cancer Institute
- Emory University
- Harvard University
- Massachusetts General Hospital
- National Cancer Institute
- National Institutes of Health
- Prostate Cancer Foundation
- United States Department of Defense
- University of California, Los Angeles