Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling
Abstract
There is increasing effort to discover and integrate predictive and/or prognostic biomarkers into treatment algorithms. While tissue-based methods can reveal tumor–immune cell compositions at a single time point, we propose that single-cell sampling via fine needle aspiration (FNA) can facilitate serial assessment of the tumor immune microenvironment (TME) with a favorable risk–benefit profile.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 07, 2021
- Source ID
- 10.1158/1078-0432.ccr-21-1252
Entities
People
- Christian Landeros
- Hakho Lee
- John R. Clark
- Jonathan C.t. Carlson
- Juhyun Oh
- Mikael Pittet
- Ralph Weissleder
- Sara I Pai
- Scott Ferguson
- William C Faquin
Organizations
- Geneva University Hospitals
- Harvard Medical School
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- University of Geneva