Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Abstract

Black men die from prostate cancer twice as often as White men, a disparity likely due to inherited genetics, modifiable cancer risk factors, and healthcare access. It is incompletely understood how and why tumor genomes differ by self-reported race and genetic ancestry.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 19, 2021
Source ID
10.1158/1078-0432.ccr-21-2577

Entities

People

  • Barbara Nweji
  • Bastien Nguyen
  • Dana E. Rathkopf
  • Daniel C. Danila
  • David B Solit
  • Howard I. Scher
  • Kanika Arora
  • Karen A. Autio
  • Konrad H Stopsack
  • Lorelei A. Mucci
  • Michael F. Berger
  • Michael J. Morris
  • Mithat Gönen
  • Nikolaus Schultz
  • Philip W. Kantoff
  • Samantha E. Vasselman
  • Sean M. Mcbride
  • Subhiksha Nandakumar
  • Susan F. Slovin
  • Wassim Abida
  • Yu Chen

Organizations

  • Harvard University
  • Memorial Sloan Kettering Cancer Center
  • National Cancer Institute
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology