Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer
Abstract
Cancer-associated fibroblasts (CAF) have been implicated as potential mediators of checkpoint immunotherapy response. However, the extensive heterogeneity of these cells has precluded rigorous understanding of their immunoregulatory role in the tumor microenvironment.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 09, 2022
- Source ID
- 10.1158/1078-0432.ccr-21-3570
Entities
People
- Abdullah B Naveed
- Adam Luginbuhl
- Aleksandar Obradovic
- Andrea Califano
- Charles G Drake
- Diana Graves
- Joseph Curry
- Kamran Idrees
- Michael K. Gibson
- Michael Korrer
- Paula Hurley
- Peng Jiang
- Ravindra Uppaluri
- Sohini Roy
- Xiaole Shirley Liu
- Yaomin Xu
- Young J Kim
- Yu Wang
Organizations
- American Cancer Society
- Brigham and Women's Hospital
- Columbia University
- Congressionally Directed Medical Research Programs
- Dana–Farber Cancer Institute
- National Cancer Institute
- National Institute of Dental and Craniofacial Research
- Thomas Jefferson University
- Vanderbilt University
- Vanderbilt University Medical Center