TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti–PD-1/anti–CTLA-4 immunotherapy

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 19, 2018
Source ID
10.1172/jci.insight.98674

Entities

People

  • Arlene Sharpe
  • Elizabeth P Henske
  • Gordon J. Freeman
  • Heng Du
  • Heng-Jia Liu
  • Hilaire C. Lam
  • Kwok-kin Wong
  • Maria C. Speranza
  • Nicola Alesi
  • Patrick H Lizotte
  • Spencer Vaughan

Organizations

  • Tuberous Sclerosis Alliance
  • United States Department of Defense

Tags

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech