In vitro hemocompatibility screening of a slippery liquid impregnated surface coating for extracorporeal organ support applications
Abstract
Clot formation, infection, and biofouling are unfortunate but frequent complications associated with the use of blood-contacting medical devices. The challenge of blood-foreign surface interactions is exacerbated during medical device applications involving substantial blood contact area and extended duration of use, such as extracorporeal life support (ECLS). We investigated a novel surface modification, a liquid-impregnated surface (LIS), designed to minimize protein adsorption and thrombus development on medical plastics.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 05, 2022
- Source ID
- 10.1177/02676591221095469
Entities
People
- Andriy I. Batchinsky
- George T. Harea
- Raymond P. Seekell
- Teryn R. Roberts
- Yanyi Zang
- Zheng Zhang
Organizations
- Congressionally Directed Medical Research Programs
- Geneva Foundation