K+ontrol rapidly and efficiently reduces potassium in donor blood during ex vivo circulation
Abstract
Patients with kidney failure are at risk for lethal complications from hyperkalemia. Resuscitation, medications, and hemodialysis are used to mitigate increased potassium (K+) levels in circulating blood; however, these approaches may not always be readily available or effective, especially in a resource limited environment. We tested a sorbent cartridge (KC, K+ontrol CytoSorbents Medical Inc., Monmouth Junction, New Jersey) which contains a resin adsorber for K+. The objective of this study was to test the utility of KC in an ex vivo circulation system. We hypothesized that KC reduces K+ levels in extracorporeal circulation of donor swine whole blood infused with KCl.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 04, 2022
- Source ID
- 10.1177/02676591221130175
Entities
People
- Andriy I. Batchinsky
- Brendan M Beely
- Daniel S. Wendorff
- George T. Harea
- Ian J Stewart
- Isabella Garcia
- Kevin K Chung
- Marianne Thrailkill
- Maryann C Gruda
- Phillip P. Chan
- Tamaz Guliashvili
- Teja Guda
- Teryn R. Roberts
- Thomas D. Golobish
- Tim Kovacs
Organizations
- Congressionally Directed Medical Research Programs
- Uniformed Services University of the Health Sciences
- University of Texas at San Antonio
- University of the Incarnate Word