The development of a mouse model of mTBI-induced post-traumatic migraine, and identification of the delta opioid receptor as a novel therapeutic target
Abstract
Post-traumatic headache is the most common and long-lasting impairment observed following mild traumatic brain injury, and frequently has migraine-like characteristics. The mechanisms underlying progression from mild traumatic brain injury to post-traumatic headache are not fully understood. The aim of this study was to develop a mouse model of post-traumatic headache and identify mechanisms and novel targets associated with this disorder.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 17, 2018
- Source ID
- 10.1177/0333102418777507
Entities
People
- Alycia F Tipton
- Amynah A Pradhan
- Harish Krishnan
- Laura S. Moye
- Madeline L Novack
- Subhash C Pandey
Organizations
- Congressionally Directed Medical Research Programs
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse
- University of Illinois at Chicago
- Veterans Health Administration