Point-of-Care Procedure for Enhancement of Meniscal Healing in a Goat Model Utilizing Infrapatellar Fat Pad–Derived Stromal Vascular Fraction Cells Seeded in Photocrosslinkable Hydrogel

Abstract

Large radial tears of the meniscus involving the avascular region can compromise meniscal function and result in poor healing and subsequent osteochondral degeneration. Augmentation of surgical repairs with adipose-derived stromal vascular fraction (SVF), which contains mesenchymal stromal cells, may improve meniscal healing and preserve function (ie, chondroprotection).

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 23, 2019
Source ID
10.1177/0363546519880468

Entities

People

  • Benjamin B Rothrauff
  • Freddie H. Fu
  • Hang Lin
  • Hiroshi Sasaki
  • Kalon J. Overholt
  • Peter G Alexander
  • Riccardo Gottardi
  • Rocky Tuan
  • Shinsuke Kihara

Organizations

  • United States Department of Defense
  • University of Pittsburgh

Tags

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Trauma Surgery or Emergency Medicine.
  • Urban Planning and Geography.