Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis

Abstract

Mesenchymal stem cells (MSCs) exhibit immunomodulatory, tissue-protective, and repair-promoting properties in vitro and in animals. Clinical trials in several human conditions support the safety and efficacy of MSC transplantation. Published experience in multiple sclerosis (MS) is modest.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 06, 2017
Source ID
10.1177/1352458517703802

Entities

People

  • Amit Bar-or
  • Elizabeth M. Fisher
  • Hillard M Lazarus
  • Jane Reese Koc
  • Jeffrey A Cohen
  • Matt Karafa
  • Patricia Jagodnik
  • Peter B Imrey
  • Robert A Bermel
  • Robert J Fox
  • Sarah M Planchon
  • Shannon Morrison
  • Stanton L. Gerson
  • Susan L Sharp
  • Thomai T Skaramagas

Organizations

  • Biogen
  • Case Western Reserve University
  • Cleveland Clinic
  • McGill University
  • National Center for Advancing Translational Sciences
  • National Institute of Neurological Disorders and Stroke
  • National Multiple Sclerosis Society
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Trauma or Military Medicine

Technology Areas

  • Biotechnology