Insights into microbiome research 5: Mapping is first but function must come next
Abstract
Several efforts identifying differential bacterial prevalence in the gut of multiple sclerosis (MS) patients have been reported and many more are underway. While these are critical first steps in determining the involvement of gut microbes in MS pathogenesis, functional assays (both in vitro and in vivo) are needed to explore the mechanisms underlying the observed changes and ultimately implementing interventional strategies to counter severity, progression or even reduce the chance that it develops in the first place.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 01, 2019
- Source ID
- 10.1177/1352458518811203
Entities
People
- Sergio E Baranzini
Organizations
- National Multiple Sclerosis Society
- United States Department of Defense
- University of California, San Francisco