Evidence of diffuse cerebellar neuroinflammation in multiple sclerosis by 11C-PBR28 MR-PET
Abstract
Activated microglia, which can be detected in vivo by 11C-PBR28 positron emission tomography (PET), represent a main component of MS pathology in the brain. Their role in the cerebellum is still unexplored, although cerebellar involvement in MS is frequent and accounts for disability progression.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 11, 2019
- Source ID
- 10.1177/1352458519843048
Entities
People
- Ambica Mehndiratta
- Carolina Ionete
- Caterina Mainero
- Costantina A Treaba
- Elena Herranz
- Eric C. Klawiter
- Marco L Loggia
- Russell Ouellette
- Sloane A Jacob
- Valeria T Barletta
Organizations
- Blueprint for Neuroscience Research
- Harvard Medical School
- Karolinska Institutet
- Massachusetts General Hospital
- National Multiple Sclerosis Society
- United States Department of Defense