Accuracy of serum neurofilament light to identify contrast-enhancing lesions in multiple sclerosis

Abstract

Contrast-enhancing magnetic resonance imaging (MRI) lesions (CELs) indicate acute multiple sclerosis inflammation. Serum biomarkers, neurofilament light (sNfL), and glial fibrillary acidic protein (sGFAP) may increase in the presence of CELs, and indicate a need to perform MRI.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 15, 2023
Source ID
10.1177/13524585231198751

Entities

People

  • Bonnie I Glanz
  • Brian C. Healy
  • Christian Barro
  • Gauruv Bose
  • Howard L. Weiner
  • Hrishikesh A. Lokhande
  • Mariann Polgar-Turcsanyi
  • Rohit Bakshi
  • Shrishti Saxena
  • Tanuja Chitnis
  • Vanessa F Moreira Ferreira

Organizations

  • Brigham and Women's Hospital
  • Harvard Medical School
  • MS Walk
  • United States Department of Defense
  • University of Ottawa

Tags

Fields of Study

  • Medicine

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Neuroscience
  • Oncology and Biomarker-Based Cancer Detection.