High-resolution 3D tractography of fibrous tissue based on polarization-sensitive optical coherence tomography
Abstract
Fibrous tissues play important roles in many parts of the body. Their highly organized directional structure is essential in achieving their normal biomechanical and physiological functions. Disruption of the typical fiber organization in these tissues is often linked to pathological changes and disease progression. Tractography is a specialized imaging method that can reveal the detailed fiber architecture. Here, we review recent developments in high-resolution optical tractography using Jones matrix polarization-sensitive optical coherence tomography. We also illustrate the use of this new tractography technology for visualizing depth-resolved, three-dimensional fibrous structures and quantifying tissue damages in several major fibrous tissues.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 08, 2019
- Source ID
- 10.1177/1535370219894332
Entities
People
- Dongsheng Duan
- Gang Yao
Organizations
- Congressionally Directed Medical Research Programs
- University of Missouri