Identifying relevant diffusion MRI microstructure biomarkers relating to exposure to repeated head impacts in contact sport athletes
Abstract
Repeated head impacts (RHI) without concussion may cause long-term sequelae. A growing array of diffusion MRI metrics exist, both empiric and modeled and it is hard to know which are potentially important biomarkers. Common conventional statistical methods fail to consider interactions between metrics and rely on group-level comparisons. This study uses a classification pipeline as a means towards identifying important diffusion metrics associated with subconcussive RHI.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 22, 2023
- Source ID
- 10.1177/19714009231177396
Entities
People
- Dmitry S Novikov
- Els Fieremans
- J. Chen
- Sohae Chung
- Tianhao Li
- Yao Wang
- Yvonne W Lui
Organizations
- National Institute of Biomedical Imaging and Bioengineering
- National Institute of Neurological Disorders and Stroke
- New York University
- United States Department of Defense