Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis

Abstract

Multiple sclerosis is an inflammatory, neurodegenerative disease of the central nervous system for which therapeutic mesenchymal stem cell transplantation is under study. Published experience of culture-expanding multiple sclerosis patients’ mesenchymal stem cells for clinical trials is limited.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2018
Source ID
10.1177/2055217318765288

Entities

People

  • Basabi Maitra
  • Brittney M Hooper
  • Hillard M Lazarus
  • Jane Reese Koc
  • Jeffrey A Cohen
  • Karen T Lingas
  • Kylie M Drake
  • Micheala A Aldred
  • Peter B Imrey
  • Robert M. Fox
  • Sarah M Planchon

Organizations

  • Case Western Reserve University
  • Genomic Medicine Institute
  • National Institute of Neurological Disorders and Stroke
  • National Multiple Sclerosis Society
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biology

Technology Areas

  • Biotechnology