The effect of mesenchymal stem cells improves the healing of burn wounds: a phase 1 dose-escalation clinical trial

Abstract

Stem cell therapy holds promise to improve healing and stimulate tissue regeneration after burn injury. Preclinical evidence has supported this; however, clinical studies are lacking. We examined the application of bone marrow-derived mesenchymal stem cells (BM-MSC) to deep second-degree burn injuries using a two-dose escalation protocol.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2022
Source ID
10.1177/20595131211070783

Entities

People

  • Ambar Candanedo
  • Audrey Beirn
  • Carl I Schulman
  • Divya Aickara
  • Eric Maranda
  • Evangelos V. Badiavas
  • Jeffrey D. Mcbride
  • Louis Pizano
  • Luis Rodriguez-Menocal
  • Nicholas Namias
  • Wellington Guzman

Organizations

  • Leonard M. Miller School of Medicine
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Immunology and Pathology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology