Retinopathy of Prematurity Screening of Preterm Infants With Icteric Vitreous

Abstract

Purpose: To present 2 cases of premature newborns with hyperbilirubinemia and retinopathy of prematurity (ROP) who could not be examined properly to assess for disease progression because of vitreous opacification in the setting of an icteric vitreous and frail health status. Methods: The cases and their findings were analyzed. Results: Given the sickness of the neonates and examination difficulty, intravitreal bevacizumab was administered in both eyes to prevent disease progression. During subsequent examinations, the patients remained stable until discharge from the neonatal intensive care unit and were followed in the outpatient clinic without complication. Conclusions: The ROP and vitreous opacification in our cases were thought to be caused by hyperbilirubinemia. Because of vitreous opacification, these patients could not be properly examined for ROP. Treatment with an intravitreal antivascular endothelial growth factor injection might be considered to delay disease development until the newborn is healthier and able to be examined.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 17, 2023
Source ID
10.1177/24741264231173206

Entities

People

  • Ashley López-Cañizares
  • Audina M. Berrocal
  • Hasenin Al-Khersan
  • Natasha Ferreira Santos da Cruz

Organizations

  • Bascom Palmer Eye Institute
  • National Institutes of Health
  • Research to Prevent Blindness
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

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