A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages

Abstract

Ontologically distinct populations of macrophages differentially contribute to organ fibrosis through unknown mechanisms.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 10, 2019
Source ID
10.1183/13993003.00646-2019

Entities

People

  • Alexander V. Misharin
  • Alexandra C McQuattie-Pimentel
  • Annette S. Flozak
  • Cara J Gottardi
  • Carla M. Cuda
  • Ching-i Chen
  • David Kirchenbuechler
  • David W. Kamp
  • G.r. Scott Budinger
  • Harris Perlman
  • Lango Sichizya
  • Manu Jain
  • Nikita Joshi
  • Nikolay S Markov
  • Paul A Reyfman
  • Paul Cheresh
  • Raul Piseaux-aillon
  • Renea P. Jablonski
  • Rohan Verma
  • Satoshi Watanabe
  • Ziyan Lu

Organizations

  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
  • National Institute on Aging
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Systems Analysis and Design