φX216, a P2-like bacteriophage with broad Burkholderia pseudomallei and B. malleistrain infectivity
Abstract
Burkholderia pseudomallei and B. mallei are closely related Category B Select Agents of bioterrorism and the causative agents of the diseases melioidosis and glanders, respectively. Rapid phage-based diagnostic tools would greatly benefit early recognition and treatment of these diseases. There is extensive strain-to-strain variation in B. pseudomallei genome content due in part to the presence or absence of integrated prophages. Several phages have previously been isolated from B. pseudomallei lysogens, for example φK96243, φ1026b and φ52237.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 01, 2012
- Source ID
- 10.1186/1471-2180-12-289
Entities
People
- Brian H Kvitko
- Christopher R. Cox
- David Deshazer
- Herbert P Schweizer
- Kent J. Voorhees
- Shannon L. Johnson