Evaluation of the potential of Pap test fluid and cervical swabs to serve as clinical diagnostic biospecimens for the detection of ovarian cancer by mass spectrometry-based proteomics
Abstract
The purpose of this study was to determine whether the residual fixative from a liquid-based Pap test or a swab of the cervix contained proteins that were also found in the primary tumor of a woman with high grade serous ovarian cancer. This study is the first step in determining the feasibility of using the liquid-based Pap test or a cervical swab for the detection of ovarian cancer protein biomarkers.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 07, 2021
- Source ID
- 10.1186/s12014-020-09309-3
Entities
People
- Amy P N Skubitz
- Kristin L. M. Boylan
- Melissa A. Geller
- Peter A. Argenta
- Somaieh Afiuni-zadeh
- Timothy J. Griffin
Organizations
- Minnesota Ovarian Cancer Alliance
- United States Department of Defense