MicroScope: ChIP-seq and RNA-seq software analysis suite for gene expression heatmaps

Abstract

Heatmaps are an indispensible visualization tool for examining large-scale snapshots of genomic activity across various types of next-generation sequencing datasets. However, traditional heatmap software do not typically offer multi-scale insight across multiple layers of genomic analysis (e.g., differential expression analysis, principal component analysis, gene ontology analysis, and network analysis) or multiple types of next-generation sequencing datasets (e.g., ChIP-seq and RNA-seq). As such, it is natural to want to interact with a heatmap’s contents using an extensive set of integrated analysis tools applicable to a broad array of genomic data types.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 22, 2016
Source ID
10.1186/s12859-016-1260-x

Entities

People

  • Bohdan B Khomtchouk
  • Claes Wahlestedt
  • James R. Hennessy

Organizations

  • Army Research Office

Tags

Fields of Study

  • Biology

Readers

  • Aerosol Science/Aerosol Physics
  • Computer Vision.
  • Molecular Genetics