ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network

Abstract

While technological advances have made it possible to profile the immune system at high resolution, translating high-throughput data into knowledge of immune mechanisms has been challenged by the complexity of the interactions underlying immune processes. Tools to explore the immune network are critical for better understanding the multi-layered processes that underlie immune function and dysfunction, but require a standardized network map of immune interactions. To facilitate this we have developed ImmunoGlobe, a manually curated intercellular immune interaction network extracted from Janeway’s Immunobiology textbook.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 10, 2020
Source ID
10.1186/s12859-020-03702-3

Entities

People

  • Edgar Engleman
  • Hunter Boyce
  • Kamir J. Hiam
  • Matthew H Spitzer
  • Michelle B. Atallah
  • Michelle Hori
  • Parag Mallick
  • Varun Tandon
  • Waleed Atallah

Organizations

  • Defense Advanced Research Projects Agency
  • National Institutes of Health

Tags

Fields of Study

  • Biology

Readers

  • Distributed Systems and Data Platform Development
  • Immunology