Exploring the functional composition of the human microbiome using a hand-curated microbial trait database
Abstract
Even when microbial communities vary wildly in their taxonomic composition, their functional composition is often surprisingly stable. This suggests that a functional perspective could provide much deeper insight into the principles governing microbiome assembly. Much work to date analyzing the functional composition of microbial communities, however, relies heavily on inference from genomic features. Unfortunately, output from these methods can be hard to interpret and often suffers from relatively high error rates.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 07, 2021
- Source ID
- 10.1186/s12859-021-04216-2
Entities
People
- Cyrus Davati
- David K. Karig
- Florian P Breitwieser
- J. L. Weissman
- Jess Beattie
- Keshav Dixit
- Keyan Javadi
- Peter Thielen
- Philip L F Johnson
- Rachel Flint
- Samantha Bolten
- Sharon Bewick
- Shehar Awan
- Sonia Dogra
- Tejasvi Peesay
- William F. Fagan
Organizations
- United States Army Research Laboratory