The maximum entropy principle for compositional data

Abstract

Compositional systems, represented as parts of some whole, are ubiquitous. They encompass the abundances of proteins in a cell, the distribution of organisms in nature, and the stoichiometry of the most basic chemical reactions. Thus, a central goal is to understand how such processes emerge from the behaviors of their components and their pairwise interactions. Such a study, however, is challenging for two key reasons. Firstly, such systems are complex and depend, often stochastically, on their constituent parts. Secondly, the data lie on a simplex which influences their correlations.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 29, 2022
Source ID
10.1186/s12859-022-05007-z

Entities

People

  • Allen R. Tannenbaum
  • Corey Weistuch
  • Jiening Zhu
  • Joseph O. Deasy

Organizations

  • Air Force Office of Scientific Research
  • Army Research Office
  • National Institutes of Health
  • The Breast Cancer Research Foundation

Tags

Readers

  • Molecular Genetics
  • Regression Analysis.
  • Theoretical Analysis.