Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer
Abstract
Reproductive characteristics are well-established risk factors for breast cancer, but the underlying mechanisms are not fully resolved. We hypothesized that altered DNA methylation, measured in tumor tissue, could act in concert with reproductive factors to impact breast carcinogenesis.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 18, 2019
- Source ID
- 10.1186/s12885-019-6120-4
Entities
People
- Alexandra J. White
- Alfred I. Neugut
- Jia Chen
- Kathleen Conway
- Lauren E McCullough
- Lindsay J. Collin
- Marilie D. Gammon
- Mary Beth Terry
- Regina M. Santella
- Sumitra Shantakumar
- Susan L. Teitelbaum
- Yoon Hee Cho
Organizations
- National Institutes of Health
- United States Department of Defense