Temporal changes in gut microbiota profile in children with acute lymphoblastic leukemia prior to commencement-, during-, and post-cessation of chemotherapy
Abstract
Alteration in gut microbiota has been recently linked with childhood leukemia and the use of chemotherapy. Whether the perturbed microbiota community is restored after disease remission and cessation of cancer treatment has not been evaluated. This study examines the chronological changes of gut microbiota in children with acute lymphoblastic leukemia (ALL) prior to the start-, during-, and following cessation of chemotherapy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 24, 2020
- Source ID
- 10.1186/s12885-020-6654-5
Entities
People
- Hany Ariffin
- Ling Ling Chua
- P'ng Loke
- Reena Rajasuriar
- Yin Ling Woo
- Yvonne Ai Lian Lim
Organizations
- Institute of Research Management and Monitoring, University of Malaya
- National Institutes of Health
- United States Department of Defense