Transcriptional landscape of PTEN loss in primary prostate cancer
Abstract
PTEN is the most frequently lost tumor suppressor in primary prostate cancer (PCa) and its loss is associated with aggressive disease. However, the transcriptional changes associated with PTEN loss in PCa have not been described in detail. In this study, we highlight the transcriptional changes associated with PTEN loss in PCa.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 26, 2021
- Source ID
- 10.1186/s12885-021-08593-y
Entities
People
- Diego Fernando Sanchez
- Eddie Luidy Imada
- Edward M. Schaeffer
- Ericka M Ebot
- Glória Regina Franco
- Lorelei Ann Mucci
- Luigi Marchionni
- Massimo Loda
- Svitlana Tyekucheva
- Tamara L Lotan
- Thiago Vidotto
- Wikum Dinalankara
Organizations
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- National Cancer Institute
- United States Department of Defense