Association between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial
Abstract
Pulmonary hypertension (PH) in COPD confers increased risk of exacerbations (ECOPD). Electrocardiogram (ECG) indicators of PH are prognostic both in PH and COPD. In the Beta-Blockers for the Prevention of Acute Exacerbations of COPD (BLOCK-COPD) trial, metoprolol increased risk of severe ECOPD through unclear mechanisms.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 09, 2023
- Source ID
- 10.1186/s12890-023-02748-2
Entities
People
- David M. Macdonald
- Erika. S. Helgeson
- Helen Voelker
- Ken M. Kunisaki
- Krystle Pew
- Mark T Dransfield
- Matthew R. Lammi
- R. Chad Wade
- Sharon X. Ling
- Takudzwa Mkorombindo
- Vera Bittner
Organizations
- United States Department of Defense