ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction
Abstract
A disintegrin and metalloproteinase domain-15 (ADAM15) is expressed by activated leukocytes, and fibroblasts in vitro. Whether ADAM15 expression is increased in the lungs of COPD patients is not known.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 16, 2020
- Source ID
- 10.1186/s12931-020-01446-5
Entities
People
- Andrew Higham
- Bartolome Celli
- Caroline A Owen
- Dave Singh
- Duo Zhang
- Edwin K. Silverman
- Hans Petersen
- Lu Zhou
- Miguel Divo
- Sophie Wolosianka
- Victor Pinto-plata
- Xiaoyan Gai
- Xiaoyun Wang
- Yongchang Sun
Organizations
- FAMRI
- National Heart, Lung, and Blood Institute
- National Institute of Allergy and Infectious Diseases
- National Natural Science Foundation of China
- United States Department of Defense