A novel large animal model of smoke inhalation-induced acute respiratory distress syndrome
Abstract
Acute respiratory distress syndrome (ARDS) is multifactorial and can result from sepsis, trauma, or pneumonia, amongst other primary pathologies. It is one of the major causes of death in critically ill patients with a reported mortality rate up to 45%. The present study focuses on the development of a large animal model of smoke inhalation-induced ARDS in an effort to provide the scientific community with a reliable, reproducible large animal model of isolated toxic inhalation injury-induced ARDS.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 07, 2021
- Source ID
- 10.1186/s12931-021-01788-8
Entities
People
- Andrea Mccain
- Ernesto Martinez Duarte
- Hannah R. Weber
- Keely Buesing
- Premila D. Leiphrakpam
- Roser Romaguera Matas
Organizations
- United States Department of Defense