Metabolic alterations in the erythrocyte during blood-stage development of the malaria parasite

Abstract

Human blood cells (erythrocytes) serve as hosts for the malaria parasitePlasmodium falciparumduring its 48-h intraerythrocytic developmental cycle (IDC). Established in vitro protocols allow for the study of host–parasite interactions during this phase and, in particular, high-resolution metabolomics can provide a window into host–parasite interactions that support parasite development.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 27, 2020
Source ID
10.1186/s12936-020-03174-z

Entities

People

  • Anders Wallqvist
  • Jaques Reifman
  • Russell P Swift
  • Sean T Prigge
  • Shivendra G Tewari

Organizations

  • Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health
  • National Center for Research Resources
  • National Institutes of Health
  • United States Army Medical Research and Development Command

Tags

Fields of Study

  • Biology

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Parasitology and Pharmacology of Malaria.