Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019
Abstract
Histidine-rich protein-2 (HRP2)-based rapid diagnostic tests (RDTs) are the only RDTs recommended for malaria diagnosis in Uganda. However, the emergence of Plasmodium falciparum histidine rich protein 2 and 3 (pfhrp2 and pfhrp3) gene deletions threatens their usefulness as malaria diagnostic and surveillance tools. The pfhrp2 and pfhrp3 gene deletions surveillance was conducted in P. falciparum parasite populations in Uganda.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 26, 2020
- Source ID
- 10.1186/s12936-020-03362-x
Entities
People
- Adoke Yeka
- Bora Lee
- Bosco B Agaba
- Chae Seung Lim
- Charles Karamagi
- Christiane Prosser
- David R. Smith
- Emmanuel Arinaitwe
- Jane Cunningham
- Jimmy Opigo
- Joan K. Nakayaga
- Joaniter I. Nankabirwa
- John Kissa
- Karen Anderson
- Karryn Gresty
- Moses R. Kamya
- Paul Mbaka
- Qin Cheng
- Rhoda Namubiru
- Sam Nsobya
- Samuel Gonahasa
- Sungho Won
Organizations
- Armed Forces Health Surveillance Center
- John E. Fogarty International Center