Clinical recovery of Macaca fascicularis infected with Plasmodium knowlesi
Abstract
Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge of the disease progression and resilience in kra monkeys will aid the effective use of this species to study mechanisms of resilience to malaria. This longitudinal study aimed to define clinical, physiological and pathological changes in kra monkeys infected with P. knowlesi, which could explain their resilient phenotype.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 30, 2021
- Source ID
- 10.1186/s12936-021-03925-6
Entities
People
- Alberto Moreno
- Allison Hankus
- Anuj Gupta
- Celia L. Saney
- Chester J Joyner
- Chris Ibegbu
- Cristiana F. A. Brito
- Dan Ory
- Dave C. Anderson
- Dean P. Jones
- Deepa Machiah
- Diego M. Moncada-giraldo
- Eberhard O. Voit
- Ebru Karpuzoglu
- Elizabeth D. Trippe
- Esmeralda V. S. Meyer
- Ferhat Ay
- Frances E. -h. Lee
- Gregory K Tharp
- Ignacio Sanz
- Jan Pohl
- Jay C. Humphrey
- Jennifer S. Wood
- Jeremy D. Debarry
- Jessica A. Brady
- Jessica C. Kissinger
- Jianlin Jiang
- Jinho Choi
- John W. Barnwell
- Juan B. Gutiérrez
- Jung-ting Chien
- Karan Uppal
- Karine Gaelle Le Roche
- Luis L. Fonseca
- Mahpic-consortium
- Maren Smith
- Mariko S. Peterson
- Mary R. Galinski
- Megan Debarry
- Monica Cabrera-mora
- Mustafa V. Nural
- Nicolas Lackman
- Rabindra Tirouvanziam
- Regina Joice Cordy
- Saeid Safaei
- Sanjeev Gumber
- Shuzhao Li
- Stacey A. Lapp
- Stephanie R. Soderberg
- Steven E Bosinger
- Susanne Warrenfeltz
- Tracey J. Lamb
- Tyrone Williams
- Vilinh Tran
- Wayne T. Cheng
- Xuntian Jiang
- Zerotti L. Woods
Organizations
- Defense Advanced Research Projects Agency
- National Institute of Allergy and Infectious Diseases