Cognitive decrements in 1991 Gulf War veterans: associations with Gulf War illness and neurotoxicant exposures in the Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) cohorts
Abstract
During deployment, veterans of the 1991 Gulf War (GW) were exposed to multiple war-related toxicants. Roughly a third of these veterans continue to exhibit neurotoxicant induced symptoms of Gulf War Illness (GWI), a multi-faceted condition that includes fatigue, pain and cognitive decrements. When studied empirically, both deployed veterans with exposures and those who meet the criteria for GWI are more likely to show deficits in the area of neuropsychological functioning. Although studies have shown cognitive impairments in small sample sizes, it is necessary to revisit these findings with larger samples and newer cohorts to see if other areas of deficit emerge with more power to detect such differences. A group of researchers and clinicians with expertise in the area of GWI have identified common data elements (CDE) for use in research samples to compare data sets. At the same time, a subgroup of researchers created a new repository to share these cognitive data and biospecimens within the GWI research community.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 04, 2023
- Source ID
- 10.1186/s12940-023-01018-2
Entities
People
- D. Keating
- E. Quinn
- J. Dugas
- Kevin M. Sullivan
- L. Steele
- Leon Chao
- Lloyd P. Janulewicz
- Maxine H Krengel
- N. Klimas
- R. Toomey
- T. Heeren
Organizations
- United States Department of Defense