LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma
Abstract
PVT1 has emerged as an oncogene in many tumor types. However, its role in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) is unknown. The aim of this study was to assess the role of PVT1 in BE/EAC progression and uncover its therapeutic value against EAC.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 10, 2019
- Source ID
- 10.1186/s12943-019-1064-5
Entities
People
- A. Robert Macleod
- Ailing W. Scott
- Brian Weston
- Chengcao Sun
- Christopher Vellano
- Chunru Lin
- Guangchun Han
- Jaffer A. Ajani
- Jeffrey H. Lee
- Jiankang Jin
- Lang Ma
- Linghua Wang
- Liuqing Yang
- Longfei Huo
- Manoop S. Bhutani
- Melissa Pool Pizzi
- Shumei Song
- Yan Xu
- Ying Wang
- Youngsoo Kim
- Yuan Li
- Zhenning Wang
Organizations
- National Cancer Institute